Placenta grades are number values assigned to a placenta on the basis of its appearance on an ultrasound examination. They reflect the placenta's age and level of maturation at the time of the exam and can provide important information about when the baby is due. A placenta that matures too quickly can be a cause for concern, as it may indicate a pregnancy complication that could threaten the health of the developing fetus. At each ultrasound session, the technician should note all findings in a report that goes into the patient's chart.

The placenta anchors to the uterine wall during fetal development and provides nutrition to the developing fetus. As the fetus grows, the placenta's characteristics will change. It initially has a very homogenous appearance, but will become dappled with dots and shadows over the course of the pregnancy. Calcifications start to develop and will show up as white marks on the ultrasound. The appearance of the placenta provides information about how old it is, and placenta grades offer a uniform way for recording information.

Grade 0 : Placental body is homogeneous. The amniochorionic plate is even throughout. Late first trimester-early second trimester.

Grade I : Placental body shows a few echogenic densities ranging from 2-4 mm in diameter. Chorionic plate shows small indentations. Mid second trimester - early third trimester (18-29 wks).

Grade II : Chorionic plate shows marked indentations,creating comma-like densities which extend into the placental substance but do not reach the basal plate. The echogenic densities within the placental also increase in size and number. The basal layer comes punctuated with linear echoes which are enlarged with their long axis parallel to the basal layer. Late third trimester (30 wks to delivery)

Grade III : Complete indentations of chorionic plate through to the basilar plate creating cotyledons (portions of placenta separated by the indentations) . (39 wks) 




On ET+5, we were told only 1 of 4 embryos able to develop to blastocyst stage, again we ended up having no embryos to freeze. Sad. However I want to be grateful as I was still blessed and cherished with our dear only blastocyst embryo.
Post embryo transfer, I was asked to lie down for 2-3 hours then I was allowed to go back home. I was scheduled on:
21st Nov – to have a routine Cyclogest 400 mg, Progynova 2 mg per vaginal at 3 pm, 11 pm and 250 mg Proluton injection
22nd Nov – 3rd Dec – Cyclogest 400 mg and Progynova 2mg per vaginal at 7 am, 3 pm and 11 pm
24th Nov, 27th Nov, 30th Nov – 250mg Proluton injection



On ET+3, we were told that from total 10 oocytes I got, 4 were immature, 6 were injected and numbers down to 4 embryos. And due to 15%-20% fragmentation, our 4 embryos are not suitable for PGD testing. Again, I was so heart-broken. We were asked to wait until ET+5 to see whether our 4 embryos should have reach blastocyst stage. However, the only down side doing a blastocyst transfer is that there may be some risk that no embryos make it over the hurdle and survive to day 5. 



Post OPU, I was allowed to rest in the recovery room for an hour or two, I think I was sedated quite deep, because DH said I was put in a deep sleep for quite a time after that. 
I don't know why, but I think I react poorly with the sedative, I got a motion sick and ended throwing up for the next three days post OPU. 



This 3rd consultation supposed to be our last scan, and here’s our schedule:
13th Nov -  Dr. S having me inject 237.5 IU Gonal-F, and Buserelin at 10 IU
14th Nov – Inject the balance unit of Gonal-F at 0.4 ml, Buserelin at 10 IU, and Ovidrel of 6500 IU at night
15th Nov – I was told to have 2 Dulcolax tablet after my last meal before 11.30 pm, and then fasting at least 6 hours before the Ovum Pick Up procedure.
16th Nov – Ovum Pick Up (OPU)